Our Expertise

The Gut-Hormone Connection

When one system falters, the other follows—until we interrupt the loop. At Rise, we specialize in breaking the vicious cycle between gut dysfunction and hormone disruption so your body can finally get back to balance.

The Gut-Hormone Feed-Forward Cycle

  • Gut Barrier Breakdown

    Gut Barrier Breakdown

    Leaky gut lets toxins slip through. Endotoxins spark system-wide inflammation.

  • Nutrient Malabsorption

    Missing raw materials for hormones. B 12, D, Zn, Mg, amino acids never make it into cells.

  • Hormone Synthesis & Receptor Loss

    Can’t build or use the hormones you need. Receptors dull; estrogen, T, insulin production stalls.

  • Systemic Hormone Imbalance

    Symptoms pile up. Hot flashes, brain fog, weight gain, insomnia, low drive.

  • Gut Motility & Microbiome Shift

    Hormone changes hit the gut back. Slower motility, low acid, dysbiosis… and the cycle restarts.

Functional Medicine Testing

Get answers with advanced labwork available in our structured programs

  • Women in perimenopause often experience increased demand for key nutrients due to hormonal fluctuations, gut dysfunction, and chronic stress. We assess levels of vitamins, minerals, and antioxidants to support energy, hormone balance, cognition, and immune resilience.

  • Bloating, constipation, IBS, and food reactivity are common in perimenopause—and often rooted in microbial imbalances. We use advanced stool testing to evaluate digestion, pathogens, inflammation, and microbiome diversity so we can restore your gut from the inside out.

  • This urine-based test gives insight into mitochondrial function, neurotransmitter balance, detox pathways, and nutrient status. It’s especially helpful for unexplained fatigue, brain fog, and chronic inflammation that don’t show up on standard labs.

  • Perimenopause is a dynamic hormonal transition, not a sudden drop. We evaluate estrogen, progesterone, testosterone, cortisol, and DHEA—often through blood testing—to understand the full picture and support natural balance or HRT when appropriate.

  • Midlife shifts can impact blood sugar, cholesterol, and blood pressure—often before symptoms appear. We assess insulin resistance, advanced lipids, and inflammation to reduce long-term risk and optimize metabolism now through Cleveland HeartLab®.

  • Your DNA can influence how you detoxify hormones, absorb nutrients, manage stress, and respond to inflammation. We use genetic insights to personalize your care plan for more effective, targeted results.

Test, don’t guess. All of our programs include access to advanced lab testing so you can understand exactly what’s driving your symptoms.

We use a targeted, whole-body approach to treatment:

  • Protein optimization and nutrition planning, nutrient repletion, relearning how to eat for optimal nutrient absorption

  • Lifestyle and stress regulation strategies to support motility

  • Digestive support (enzymes, stomach acid, bile flow)

  • Gut healing nutrients (L-glutamine, colostrum, zinc carnosine)

  • Targeted microbiome support (antimicrobials, prebiotics, postbiotics, probiotics)

  • Bioidentical hormone therapy (estrogen, progesterone, testosterone)

  • Compounds to repair gut and reduce inflammation like peptides and low dose naltrexone (LDN)

A Healthy Gut is the Foundation for Hormone Optimization

By restoring gut integrity, reducing inflammation, and ensuring optimal nutrient absorption, we lay the groundwork for balanced hormones, steady energy, healthy metabolism, and a resilient nervous system.

This is what we do at Rise. Let’s get started with your Elemental Assessment today.